PCL30%+CMC70%
💡 Full customization support is offered for handles, rods and tubes. We provide localized solutions with specialized versions crafted for the European, Middle Eastern and Asian regions.
PCL30%+CMC70%
Product efficacy
Long term maintenance/Collagen regeneration/Instant shaping/Highlight freeze
Product introduction
PCL MICROSPHERES
PCL is a non-toxic medical polyester, first synthesised in the early 1930s4, that is attractive for use in dermal fillers because of its ease of bioresorption; it is naturally hydrolysed into carbon dioxide and waterwithin the body5
The PCL microspheres used in are designed to offer optimal biocompatibility6. They have a smooth surface, a spherical shape and a size of approximately 25–50 μm.
PCL has an excellent safety profile3 and has been used in the biomedical field for more than 70 years for a range of applications, from sutures to tissue and organ replacements by 3D printing.
It is also used in CE-marked and US Food and Drug Administration (FDA)-approved products.
PROPERTIES OF CMC
CMC is a natural material derived from cellulose; it is not cross-linked, and is non-toxic.Its other properties include :
It is a recognised pharmaceutical excipient
It is hygroscopic
It has been designated by the FDA as generally recognised as safe (GRAS)
Resorption occurs in 2–3 months
Unique composition
is composed of a unique, patented blend of:
70% carboxymethyl cellulose (CMC)-based gel carrier 30% polycaprolactone (PCL) microspheres.
The PCL microspheres are held in homogeneous suspension in the CMC-based gel carrier. PCL and CMC both have an excellent and proven biocompatibility profile.
Bach and inflammation
The physical properties of Bach differ from those of other dermal fillers on the market in three key ways:
- Size and volume of particles: Bach PCL microspheres technology was designed to maintain the volume of the particles for a longer time, delaying the triggering of phagocytosis and intensity of the inflammatory reaction.
- Particle morphology: As the PCL microspheres can maintain their shape and smooth surface during the hydrolysis process, there is reduced risk, and decreased intensity, of secondary inflammation.
- Surface area: By maintaining the integrity of the PCL microspheres, the inflammatory reaction responsible for collagen production is sustained at a low intensity, promoting the synthesis of a more mature and organised collagen layer.
Duration of inflammation
Bach maintains its integrity over time, with the PCL microspheres triggering a low-intensity inflammatory reaction that induces neocollagenesis, which favours the more lasting type I collagen4. The end result is the long-lasting aesthetic improvement seen with Bach of up to 24 months.
